The Everglades is a natural region of tropical wetlands in the southern portion of the U.S. state of Florida, comprising the southern half of a large drainage basin and part of the neotropic ecozone. The system begins near Orlando with the Kissimmee River, which discharges into the vast but shallow Lake Okeechobee. Water leaving the lake in the wet season forms a slow-moving river 60 miles (97 km) wide and over 100 miles (160 km) long, flowing southward across a limestone shelf to Florida Bay at the southern end of the state. The Everglades experience a wide range of weather patterns, from frequent flooding in the wet season to drought in the dry season. The Seminole Tribe gave the large body of water the name Okeechobee meaning "River of Grass" to describe the sawgrass marshes, part of a complex system of interdependent ecosystems that include cypress swamps, the estuarine mangrove forests of the Ten Thousand Islands, tropical hardwood hammocks, pine rockland, and the marine environment of Florida Bay.Human habitation in the southern portion of the Florida peninsula dates to 15,000 years ago. Before European colonization, the region was dominated by the native Calusa and Tequesta tribes. With Spanish colonization, both tribes declined gradually during the following two centuries. The Seminole, formed from mostly Creek people who had been warring to the North, assimilated other peoples and created a new culture after being forced from northern Florida into the Everglades during the Seminole Wars of the early 19th century. After adapting to the region, they were able to resist removal by the United States Army.

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